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Symbol Name ID |
E2f1
E2F transcription factor 1 MGI:101941 |
| Darker colors indicate more annotations |
| Mouse Phenotypes | decreased T cell proliferation |
salivary gland inflammation |
increased thymus weight |
enlarged thymus |
increased thymocyte number |
insulitis |
abnormal double-positive T cell morphology |
decreased double-positive T cell number |
increased CD4-positive, alpha-beta T cell number |
increased CD8-positive, alpha-beta T cell number |
decreased regulatory T cell number |
increased T cell number |
abnormal CD4-positive, alpha beta T cell morphology |
abnormal CD8-positive, alpha beta T cell morphology |
increased interferon-gamma secretion |
increased interleukin-4 secretion |
increased susceptibility to autoimmune diabetes |
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| Availability | Mouse Genotype | |||||||||||||||||
| E2f1tm1Meg/E2f1tm1Meg | ||||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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